Beta Blockers Block Tumor Cell Reactivation induced by Stress Hormones

HBI Blog / Beta Blockers Block Tumor Cell Reactivation induced by Stress Hormones

Researchers from several institutions in the U.S. and one in Germany, working with AstraZeneca, have found that natural stress hormones can reactivate cancer cells that were lying dormant in mice.

Hormones

The results were published in the journal Science Translational Medicine.

Prior studies have shown that such dormant cells can awaken suddenly and start growing into a new tumor – sometimes years later.

The researchers have found the mechanism behind the awakening of the dormant cells, which is directly linked to stress hormones like norepinephrine.

As a possible solution, researchers have suggested that giving cancer patients beta-blockers might prove to be effective in preventing the awakening of the dormant tumor cells.

 Besides, drugs that can block the production of S100A8/A9 (proteins released by norepinephrine) can also prove to be a great approach.

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