Can Brain Heal Inherited Blindness?

HBI Blog / Can Brain Heal Inherited Blindness?

This discovery is like a ray of light for visually impaired individuals. A recent study revealed that the adult brain can partially heal itself from inherited blindness. 

It all started while looking for a treatment option for LCA, or Leber congenital amaurosis. It is a class of inherited retinal diseases that are defined by significant birth vision impairment. The disorder leads to the degeneration of photoreceptors in the retina and is caused by mutations in any one of more than two dozen genes.

The great discovery for blindness

LCA can be treated with chemical compounds called synthetic retinoids that target the retina in children. This can restore the vision by a lot. But this treatment is only limited to children and does not affect adults. The researchers set out to find if this treatment procedure is viable for adults with LCA or not. 

The long-awaited results

Researchers witnessed a miracle unfold in front of their eyes as the study started to show promising results. The most noticeable improvements were observed in brain circuits that are involved in vision this included the central visual pathway.

The restoration of visual function at the level of the brain was far larger than anticipated than the improvements observed at the retinal level. The fact that this therapy is so effective in the adult central visual pathway supports the idea that there is untapped potential for the vision restoration that is just waiting to be activated.

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