Metals that heal Fungal Infections

HBI Blog / Metals that heal Fungal Infections
Fungal Infections

A huge scope of developing innovative drugs has just been unlocked with this study. Evaluating on, how certain special metals in chemical compounds can potentially heal deadly fungal infections. With 1 billion people contracting a fungal infection and 1.5 million dying each year, a call for a new drug was indeed needed. 

Developing new drugs each time becomes a challenge with the discovery of every new fungal strain that is already resistant to the available drug. Currently, only a dozen clinical trials are being done with new agents to find a possible cure to these increasing numbers of fungal diseases.

The Wondrous Metals for Fungal Infections

Not just one or two, but 21 highly active metal compounds were put to test against several resistant fungal strains. Some of these metals are cobalt, nickel, rhodium, palladium, silver, europium, iridium, platinum, molybdenum, and gold. The results are as follows.

  • Many metals performed well against all fungal strains and were 30 thousand times more active against these fungi cells.
  • The topmost active compounds were then tested on the larvae of wax moths. Only one metal showed toxicity while others were well tolerated by the larvae. 
  • Finally, these metals were tested on an infectious model. Only one compound was found to be effective.

The Bigger Picture

The use of metals is not new in the healthcare industry. For instance, a platinum-containing drug Cisplatin is widely used for cancer. The promising results from this study pave the way to a future with hyper-effective antibiotics derived from metals. Yet again, it was proven that the potential of the periodic table is truly infinite.

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